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Win98
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DOS
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This file was processed as: Mailbox/MIME Entity
(archive/mbox).
| Confidence | Program | Detection | Match Type | Support
|
|---|
| 100%
| dexvert
| Mailbox/MIME Entity (archive/mbox)
| magic
| Supported |
| 1%
| dexvert
| Text File (text/txt)
| fallback
| Supported |
| 100%
| file
| Mailbox text, 1st line "From Hallucinogens: Neurochemical, Behavioural, and clinical Perspecives,", ASCII text
| default
| |
| 100%
| checkBytes
| Printable ASCII
| default
| |
| 100%
| perlTextCheck
| Likely Text (Perl)
| default
| |
| 100%
| siegfried
| x-fmt/111 Plain Text File
| default
| |
| 100%
| detectItEasy
| Format: plain text[LF]
| default (weak)
| |
| 100%
| xdgMime
| application/mbox
| default
|
|
hex view+--------+-------------------------+-------------------------+--------+--------+
|00000000| 46 72 6f 6d 20 48 61 6c | 6c 75 63 69 6e 6f 67 65 |From Hal|lucinoge|
|00000010| 6e 73 3a 20 4e 65 75 72 | 6f 63 68 65 6d 69 63 61 |ns: Neur|ochemica|
|00000020| 6c 2c 20 42 65 68 61 76 | 69 6f 75 72 61 6c 2c 20 |l, Behav|ioural, |
|00000030| 61 6e 64 20 63 6c 69 6e | 69 63 61 6c 20 50 65 72 |and clin|ical Per|
|00000040| 73 70 65 63 69 76 65 73 | 2c 0a 65 64 69 74 65 64 |specives|,.edited|
|00000050| 20 62 79 20 42 2e 20 4c | 2e 20 4a 61 63 6f 62 73 | by B. L|. Jacobs|
|00000060| 2e 20 52 61 76 65 6e 20 | 50 72 65 73 73 2c 20 4e |. Raven |Press, N|
|00000070| 65 77 20 59 6f 72 6b 20 | 28 43 29 20 31 39 38 34 |ew York |(C) 1984|
|00000080| 0a 0a 4d 65 64 69 63 69 | 6e 61 6c 20 43 68 65 6d |..Medici|nal Chem|
|00000090| 69 73 74 72 79 20 61 6e | 64 20 53 74 72 75 63 74 |istry an|d Struct|
|000000a0| 75 72 65 20 41 63 74 69 | 76 69 74 79 20 52 65 6c |ure Acti|vity Rel|
|000000b0| 61 74 69 6f 6e 73 68 69 | 70 73 20 6f 66 20 48 61 |ationshi|ps of Ha|
|000000c0| 6c 6c 75 63 69 6e 6f 67 | 65 6e 73 0a 44 61 76 69 |llucinog|ens.Davi|
|000000d0| 64 20 45 2e 20 4e 69 63 | 68 6f 6c 73 20 61 6e 64 |d E. Nic|hols and|
|000000e0| 20 52 69 63 68 61 72 64 | 20 41 2e 20 47 6c 65 6e | Richard| A. Glen|
|000000f0| 6e 6f 6e 0a 0a 50 61 67 | 65 20 31 32 33 2d 31 32 |non..Pag|e 123-12|
|00000100| 34 0a 54 68 65 20 35 2d | 68 79 64 72 6f 78 79 20 |4.The 5-|hydroxy |
|00000110| 64 65 72 72 69 76 61 74 | 69 76 65 20 6f 66 20 44 |derrivat|ive of D|
|00000120| 4d 54 2c 20 62 75 66 6f | 74 65 6e 69 6e 65 2c 20 |MT, bufo|tenine, |
|00000130| 6f 72 20 4e 2c 4e 2d 64 | 69 6d 65 74 68 79 6c 2d |or N,N-d|imethyl-|
|00000140| 73 65 72 6f 74 6f 6e 69 | 6e 2c 0a 69 73 20 61 6e |serotoni|n,.is an|
|00000150| 6f 74 68 65 72 20 6e 61 | 74 75 72 61 6c 6c 79 20 |other na|turally |
|00000160| 6f 63 63 75 72 69 6e 67 | 20 74 72 79 70 74 61 6d |occuring| tryptam|
|00000170| 69 6e 65 20 66 6f 75 6e | 64 20 74 6f 20 6f 63 63 |ine foun|d to occ|
|00000180| 75 72 20 69 6e 20 53 6f | 75 74 68 0a 41 6d 65 72 |ur in So|uth.Amer|
|00000190| 69 63 61 6e 20 53 6e 75 | 66 66 73 20 28 61 6c 73 |ican Snu|ffs (als|
|000001a0| 6f 20 42 75 66 6f 29 2e | 20 49 6e 74 72 61 76 65 |o Bufo).| Intrave|
|000001b0| 6e 6f 75 72 73 20 61 64 | 6d 69 6e 69 73 74 72 61 |nours ad|ministra|
|000001c0| 74 69 6f 6e 20 6f 66 20 | 6f 66 0a 62 75 66 6f 74 |tion of |of.bufot|
|000001d0| 65 6e 69 6e 65 20 77 61 | 73 20 72 65 70 6f 72 74 |enine wa|s report|
|000001e0| 65 64 20 62 79 20 46 61 | 62 69 6e 67 20 61 6e 64 |ed by Fa|bing and|
|000001f0| 20 63 6f 2d 77 6f 72 6b | 65 72 73 20 28 35 39 2c | co-work|ers (59,|
|00000200| 36 30 29 20 74 6f 20 62 | 65 20 0a 68 61 6c 6c 75 |60) to b|e .hallu|
|00000210| 63 69 6e 6f 67 65 6e 69 | 63 20 69 6e 20 6d 61 6e |cinogeni|c in man|
|00000220| 2e 20 54 48 69 73 20 66 | 69 6e 64 69 6e 67 20 69 |. THis f|inding i|
|00000230| 73 20 69 6e 20 63 6f 6e | 66 6c 69 63 74 20 77 69 |s in con|flict wi|
|00000240| 74 68 20 61 20 6c 61 74 | 65 72 0a 72 65 70 6f 72 |th a lat|er.repor|
|00000250| 74 20 62 79 20 54 75 72 | 6e 65 72 20 61 6e 64 20 |t by Tur|ner and |
|00000260| 4d 65 72 6c 69 73 20 28 | 32 35 33 29 2e 20 41 70 |Merlis (|253). Ap|
|00000270| 70 61 72 61 6e 74 6c 79 | 2c 20 64 75 65 20 74 6f |parantly|, due to|
|00000280| 20 69 74 73 20 6c 6f 77 | 0a 6c 69 70 69 64 20 73 | its low|.lipid s|
|00000290| 6f 6c 75 62 69 6c 69 74 | 79 20 28 36 35 29 2c 20 |olubilit|y (65), |
|000002a0| 62 75 66 6f 74 65 6e 69 | 6e 65 20 64 6f 65 73 20 |bufoteni|ne does |
|000002b0| 6e 6f 74 20 72 65 61 64 | 69 6c 79 20 63 72 6f 73 |not read|ily cros|
|000002c0| 73 20 74 68 65 0a 62 6c | 6f 6f 64 2d 62 72 61 69 |s the.bl|ood-brai|
|000002d0| 6e 20 62 61 72 72 69 65 | 72 20 28 36 34 2c 31 38 |n barrie|r (64,18|
|000002e0| 33 29 2e 20 54 68 65 20 | 69 6e 69 74 69 61 6c 20 |3). The |initial |
|000002f0| 6f 62 73 65 72 76 61 74 | 69 6f 6e 73 20 6d 61 64 |observat|ions mad|
|00000300| 65 20 62 79 0a 46 61 62 | 69 6e 67 20 65 74 2e 61 |e by.Fab|ing et.a|
|00000310| 6c 2e 20 28 35 39 2c 36 | 30 29 20 6d 61 79 20 62 |l. (59,6|0) may b|
|00000320| 65 20 74 68 65 20 72 65 | 73 75 6c 74 20 6f 66 20 |e the re|sult of |
|00000330| 70 65 72 69 70 68 65 72 | 61 6c 20 74 6f 78 69 63 |peripher|al toxic|
|00000340| 0a 6d 61 6e 69 66 65 73 | 74 61 74 69 6f 6e 73 2e |.manifes|tations.|
|00000350| 0a 09 42 75 66 6f 74 65 | 6e 69 6e 65 20 68 61 73 |..Bufote|nine has|
|00000360| 20 62 65 65 6e 20 66 6f | 75 6e 64 20 74 6f 20 62 | been fo|und to b|
|00000370| 65 20 62 65 68 76 69 6f | 75 72 61 6c 6c 79 20 69 |e behvio|urally i|
|00000380| 6e 61 63 74 69 76 65 2c | 0a 6f 72 20 6f 6e 6c 79 |nactive,|.or only|
|00000390| 20 77 65 61 6b 6c 79 20 | 61 63 74 69 76 65 20 69 | weakly |active i|
|000003a0| 6e 20 6d 6f 73 74 20 61 | 6e 69 6d 61 6c 73 20 73 |n most a|nimals s|
|000003b0| 74 75 64 69 65 73 2e 2e | 2e 0a 0a |tudies..|... |
+--------+-------------------------+-------------------------+--------+--------+
